Viral Hepatitis and Liver Cancer: Novel Paradigms and Positioning of the Institut Pasteurin


Dr. Christian Bréchot, President of Institut Pasteur, professor of liver disease and infectious disease at the University Paris Descartes was invited to attend the CAMS & PUMC Master Forum and gave a lecture titled “Viral Hepatitis and Liver Cancer” Novel Paradigms and Positioning of the Institut Pasteur on the morning of January 18, 2016. Dr. Xuetao Cao, President of CAMS & PUMC hosted the forum and 200 people including scientists, researchers and students attended.


President Xuetao Cao firstly introduced Professor Bréchot’s education and research background to the audience. Professor Bréchot was born in 1952. Since 1979, he has started his research on HBV in Institut Pasteur and got his PhD in 1985. In the next few decades, Dr. Bréchot successively worked as the Director of Liver Disease Department and the Lab in the University Paris Descartes, and President of the Biomedical Research Institute of French National Institute of Health and Medical Research (INSERM) etc. He has become the President of Institut Pasteur since October 2013. Meanwhile as a consultant to the WHO, he has made significant contribution to worldwide prevention of viral hepatitis. Professor Bréchot has made tremendous research achievements. Since 2005, he has published 400 medical theses in top world class medical journals including the Nature, the Lancet and the NEJM. H index 90. He has 18 patents for invention and is renowned in the world.  


In his lecture, Dr. Bréchot shared his latest research results and his own thoughts on viral hepatitis and liver cancer. Viral hepatitis is an infectious disease existing around the world and is closely linked with liver cancer occurrence. Over the years, Dr. Bréchot and his team have been focusing on the study of viral hepatitis and liver cancer occurrence. In the early years, they found that HBV insert and integration in the liver cancer cell genome could trigger certain oncogene. In recent years, they found that special immune microenvironment induced by HBV could lead to liver cancer. These findings have provided significant references to liver cancer treatment. Dr. Bréchot also mentioned that the occurrence of liver cancer was a complex process due to many reasons, including mutation induced by virus, changes of immune microenvironment of the liver, varied metabolism of the body and intestinal flora participation. In the end, Dr. Bréchot talked about the international development strategies and models of Institut Pasteur. After the speech, the audience raised many questions and had a heated discussion with him. 


In order to honor Dr. Bréchot for his tremendous contribution in medical science and for promoting the cooperation between CAMS & PUMC and Institut Pasteur , President Xuetao Cao granted the title of Honorary Professor of Peking Union Medical College and awarded a certificate to Dr. Bréchot on behalf of CAMS & PUMC, welcomed him to visit again each year for research and education, and hoped he continue to promote the exchange and cooperation of medical science between China and France thus make further contribution to world medical science development.


(International Cooperation Department)