Dequan Yu 



Chinese Society of Engineering

Professor Dequan Yu, male, of Han nationality, was born in Oct. 1932 in Penglai, Shandong Province. He’s a researcher with the Institute of Materia Medica of CAMS and PUMC and a doctoral supervisor. He was admitted as an academician of the Chinese Academy of Engineering in 1999.

He graduated from the major of Medicinal Chemistry in the Department of Pharmacy of Beijing Medical College (now the College of Pharmacy, Peking University Health Science Center) in 1956, then was appointed to the Department of Materia Medica in the Central Health Institute (the Institute of Materia Medica today) to work in Chemical Research Lab for Natural Products in the Institute and successively serving as research intern, assistant researcher, associate researcher and researcher.

Yu is mainly engaged in researches of natural pharmaceutical chemistry and new medicine development. He’s completed the study of chemical components in nearly 100 types of Chinese herbs and found hundreds of new compounds and defined their structures. During development of antimalarial in the 1960s, he and his colleagues found yingzhaosu A from artabotrys plants, which features evident anti-malarial effect; they also found that the peroxy bond in the molecule is the effective anti-malarial group, thus providing an example for proving the structure of artemisinin found later. The research into anti-malarial medicine used to win the “Award for Group Making Significant Contribution” co-granted by four state ministries and commissions.

Professor Dequan Yu co-hosted and completed National Key Science and Technology Project “Muskone”, raising the principle of making the formula of muskone and designing the formulation scheme. He helped solve technical problems in the research and production about chemical research, formula design, production process and quality control. He also made systematic researches into formulation of major effective constituents in muskone. Now muskone has been put into production with a cumulative output value as high as 4 billion, thus alleviating the shortage of natural musk and achieving substantial social and economic benefits. With such significance in scientific value, social benefits and eco-profit, the project won the first place in Traditional Chinese Medicine Science and Technology Progress Award of State Administration of TCM in 1997, and “Muskone Deveopment and Industrialization” won the first place in National Science and Technology Progress Award in 2015.

Professor Dequan Yu also made great efforts in studying the chemical components in traditional Chinese medicine with systematic research of the chemical components of ligusticum sinense oliver, annona squamosa and acorus gramineus, winning the second place in Science and Technology Progress Award of the Ministry of Health in 1998 and 1999, and the second place in Natural Science Award of the Ministry of Education and the first place in Beijing Science and Technology Award in 2012.

Researcher Dequan Yu took the lead in China to adopt modern 2D NMR technology to study chemical structures of natural products and promote its application, and made contributions to the introduction and wide application of other spectral analysis methods. He edited and published Nuclear Magnetic Resonance Spectroscopy (winning the first place in Excellent Books Selection of the Ministry of Chemical Industry and nomination for 2001 National Book Award), Application of Ultraviolet Spectrum in Organic Chemistry, Advances in Natural Product Chemistry and Brief Biography of Chinese Science and Technology Experts, and translated Concise Structure of Modern NMR.

In addition, Yu had more than 340 papers published, got 11 patents and edited six volumes of science and technology reference books. He trained more than 50 graduates and supervises four post-doctors. He won Capital Labor Medal in 1999 and was entitled “National Outstanding Worker” in 2000; in 1999, he was granted “20th Century Elite Award” by International Biographical Center, Cambridge; in 2001, he was listed among “Scientists who contributed to the modernization of Traditional Chinese Medicine” by Qiu Shi Science and Technologies Foundation; in 2014, he won in the Fifth National Outstanding Technical Professionals Selection.